RDH8 Antikörper (Middle Region)

Produktnummer ABIN2790129

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch RDH8 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Schwein, Kaninchen, Ratte, Rind (Kuh), Hund, Meerschweinchen und Pferd.

Kurzübersicht für RDH8 Antikörper (Middle Region) (ABIN2790129)

Target: RDH8 (Retinol Dehydrogenase 8 (RDH8))

Reaktivität: Human, Maus, Schwein, Kaninchen, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RDH8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RDH8 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: RDH8 Antibody - middle region

Sequenz: FDTNFFGAVR LVKAVLPGMK RRRQGHIVVI SSVMGLQGVI FNDVYAASKF

Homologie: Cow: 93%, Dog: 92%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RDH8. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human RDH8

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65373-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu RDH8

Target: RDH8 (Retinol Dehydrogenase 8 (RDH8))

Andere Bezeichnung: RDH8

Hintergrund:

Background Information: All-trans-retinol dehydrogenase (RDH8) is a visual cycle enzyme that reduces all-trans-retinal to all-trans-retinol in the presence of NADPH (Rattner et al., 2000 [PubMed 10753906]). It is a member of the short chain dehydrogenase/reductase family and is located in the outer segments of photoreceptors, hence it is also known as photoreceptor retinol dehydrogenase. It is important in the visual cycle by beginning the rhodopsin regeneration pathway by reducing all-trans-retinal, the product of bleached and hydrolysed rhodopsin.

Gene Name: Retinol dehydrogenase 8 (all-trans)

Alternative Symbols: PRRDH, SDR28C2

Protein Name: Retinol dehydrogenase 8

Molekulargewicht: 34 kDa

Gen-ID: 50700

NCBI Accession: NP_056540

UniProt: Q9NYR8