NANS Antikörper (C-Term)

Produktnummer ABIN2790121

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch NANS in WB. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Rind (Kuh), Hund, Kaninchen und Schwein.

Kurzübersicht für NANS Antikörper (C-Term) (ABIN2790121)

Target: NANS (N-Acetylneuraminic Acid Synthase (NANS))

Reaktivität: Human, Ratte, Rind (Kuh), Hund, Kaninchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NANS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NANS Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: NANS Antibody - C-terminal region

Sequenz: DMLTVKVGEP KGYPPEDIFN LVGKKVLVTV EEDDTIMEEL VDNHGKKIKS

Homologie: Cow: 86%, Dog: 79%, Human: 100%, Pig: 86%, Rabbit: 79%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against NANS. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65353-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu NANS

Target: NANS (N-Acetylneuraminic Acid Synthase (NANS))

Andere Bezeichnung: NANS

Hintergrund:

Background Information: This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively, however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant.

Gene Name: N-acetylneuraminic acid synthase

Alternative Symbols: SAS, SEMDG, SEMDCG, HEL-S-100

Protein Name: Sialic acid synthase

Molekulargewicht: 40kDa

Gen-ID: 54187

NCBI Accession: NP_061819

UniProt: Q9NR45