BRCA1-A Complex Subunit Abraxas 1 (ABRAXAS1) (C-Term) Antikörper

Produktnummer ABIN2790106

Der Kaninchen Polyklonal anti-BRCA1-A Complex Subunit Abraxas 1 Antikörper wird verwendet zum Nachweis von BRCA1-A Complex Subunit Abraxas 1 in Proben von Human, Kaninchen, Schwein, Pferd, Hund und Rind (Kuh). Er wurde validiert für WB.

Kurzübersicht für BRCA1-A Complex Subunit Abraxas 1 (ABRAXAS1) (C-Term) Antikörper (ABIN2790106)

Target: BRCA1-A Complex Subunit Abraxas 1 (ABRAXAS1)

Reaktivität: Human, Kaninchen, Schwein, Pferd, Hund, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails

Bindungsspezifität: C-Term

Verwendungszweck: ABRAXAS1 Antibody - C-terminal region

Sequenz: DDRWQFKRSR LLDTQDKRSK ADTGSSNQDK ASKMSSPETD EEIEKMKGFG

Homologie: Cow: 85%, Dog: 79%, Horse: 100%, Human: 100%, Pig: 79%, Rabbit: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against FAM175A. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65319-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Antigendetails

Target: BRCA1-A Complex Subunit Abraxas 1 (ABRAXAS1)

Andere Bezeichnung: ABRAXAS1

Hintergrund:

Targeted Subunit: Abraxas

Background Information: This gene encodes a protein that binds to the C-terminal repeats of breast cancer 1 (BRCA1) through a phospho-SXXF motif. The encoded protein recruits ubiquitin interaction motif containing 1 protein to BRCA1 protein and is required for DNA damage resistance, DNA repair, and cell cycle checkpoint control. Pseudogenes of this gene are found on chromosomes 3 and 8. Alternative splicing results in multiple transcript variants.

Gene Name: abraxas 1, BRCA1 A complex subunit

Alternative Symbols: ABRA1, CCDC98, FAM175A

Protein Name: BRCA1-A complex subunit Abraxas 1

Molekulargewicht: 47kDa

Gen-ID: 84142

NCBI Accession: NP_620775

UniProt: Q6UWZ7