TBXAS1 Antikörper (C-Term)

Produktnummer ABIN2790095

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch TBXAS1 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Schwein, Pferd, Rind (Kuh), Hund, Meerschweinchen und Kaninchen.

Kurzübersicht für TBXAS1 Antikörper (C-Term) (ABIN2790095)

Target: TBXAS1 (thromboxane A Synthase 1 (Platelet) (TBXAS1))

Reaktivität: Human, Ratte, Schwein, Pferd, Rind (Kuh), Hund, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TBXAS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TBXAS1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: TBXAS1 Antibody - C-terminal region

Sequenz: GYEIITNTLS FATYLLATNP DCQEKLLREV DVFKEKHMAP EFCSLEEGLP

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 79%, Pig: 100%, Rabbit: 86%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against TBXAS1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human TBXAS1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65284-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu TBXAS1

Target: TBXAS1 (thromboxane A Synthase 1 (Platelet) (TBXAS1))

Andere Bezeichnung: TBXAS1

Hintergrund:

Background Information: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative Symbols: TS, TXS, CYP5, THAS, TXAS, CYP5A1, GHOSAL, BDPLT14

Protein Name: Thromboxane synthase EMBL AAA60617.1

Molekulargewicht: 52kDa

Gen-ID: 6916

NCBI Accession: NP_112246

UniProt: Q16843