SNX6 Antikörper (Middle Region)

Produktnummer ABIN2790092

Produktdetails anti-SNX6 Antikörper

Target: SNX6 (Sorting Nexin 6 (SNX6))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Hund, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNX6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: DGVIVSGVKD VDDFFEHERT FLLEYHNRVK DASAKSDRMT RSHKSAADDY

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against SNX6. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human SNX6

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 418 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SNX6

Target: SNX6 (Sorting Nexin 6 (SNX6))

Andere Bezeichnung: SNX6 (SNX6 Produkte)

Hintergrund: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associates with the long isoform of the leptin receptor, the transforming growth factor-beta family of receptor serine-threonine kinases, and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor. This protein may form oligomeric complexes with family member proteins through interactions of both the PX domain and the coiled coil regions of the molecules. Translocation of this protein from the cytoplasm to the nucleus occurs after binding to proviral integration site 1 protein. This gene results in two transcripts encoding two distinct isoforms.
Alias Symbols: MGC3157, MSTP010, TFAF2
Protein Interaction Partner: UBC, FAM129B, VPS35, VPS29, RTF1, ATG7, TSNAX, TSN, STAT1, SNX2, SHMT2, SHMT1, PAWR, H3F3A, GTF2A1, ATP6V1C1, APEH, ANP32E, CSNK2A2, SNX1, BRCA1, PHLPP1, COIL, GIT1, ELAVL1, NDEL1, DISC1, TNIK, CALM1, TPT1, SNX6, SNX4, BMPR1B, ACVR2B, ACVRL1, LEPR, TGFBR2
Protein Size: 418

Molekulargewicht: 48 kDa

Gen-ID: 58533

NCBI Accession: NM_152233, NP_689419

UniProt: Q9UNH7

Pathways: EGFR Signaling Pathway