FKBP1A Antikörper (N-Term)

Produktnummer ABIN2790064

Der Kaninchen Polyklonal anti-FKBP1A Antikörper (ABIN2790064) detektiert spezifisch FKBP1A in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd, Saccharomyces cerevisiae und Zebrafisch (Danio rerio).

Kurzübersicht für FKBP1A Antikörper (N-Term) (ABIN2790064)

Target: FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FKBP1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FKBP1A Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: FKBP1A Antibody - N-terminal region

Sequenz: GQTCVVHYTG MLEDGKKFDS SRDRNKPFKF MLGKQEVIRG WEEGVAQMSV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 93%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against FKBP1A. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65167-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu FKBP1A

Target: FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

Andere Bezeichnung: FKBP1A

Hintergrund:

Background Information: The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.

Gene Name: FK506 binding protein 1A, 12 kDa

Alternative Symbols: FKBP1, PKC12, PKCI2, FKBP12, PPIASE, FKBP-12, FKBP-1A

Protein Name: Peptidyl-prolyl cis-trans isomerase FKBP1A

Molekulargewicht: 12kDa

Gen-ID: 2280

NCBI Accession: NP_000792

UniProt: P62942

Pathways: Negative Regulation of Transporter Activity, Methionine Biosynthetic Process