BDKRB1 Antikörper (C-Term)

Produktnummer ABIN2790059

Der Kaninchen Polyklonal anti-BDKRB1 Antikörper wird verwendet zum Nachweis von BDKRB1 in Proben von Human und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für BDKRB1 Antikörper (C-Term) (ABIN2790059)

Target: BDKRB1 (Bradykinin Receptor B1 (BDKRB1))

Reaktivität: Human, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BDKRB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BDKRB1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: BDKRB1 Antibody - C-terminal region

Sequenz: NFFAFTNSSL NPVIYVFVGR LFRTKVWELY KQCTPKSLAP ISSSHRKEIF

Homologie: Human: 100%, Rabbit: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against BDKRB1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65156-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu BDKRB1

Target: BDKRB1 (Bradykinin Receptor B1 (BDKRB1))

Andere Bezeichnung: BDKRB1

Hintergrund:

Background Information: Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene.

Gene Name: Bradykinin receptor B1

Alternative Symbols: B1R, BKR1, B1BKR, BKB1R, BRADYB1

Protein Name: B1 bradykinin receptor

Molekulargewicht: 40kDa

Gen-ID: 623

NCBI Accession: NP_000701

UniProt: P46663

Pathways: ACE Inhibitor Pathway