TNK1 Antikörper (C-Term)

Produktnummer ABIN2790058

Produktdetails anti-TNK1 Antikörper

Target: TNK1 (Tyrosine Kinase, Non-Receptor, 1 (TNK1))

Bindungsspezifität: C-Term

Reaktivität: Human, Meerschweinchen, Schwein, Kaninchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EIRQARAVPQ GPPGLPPRPP LSSSSPQPSQ PSRERLPWPK RKPPHNHPMG

Homologie: Guinea Pig: 83%, Human: 100%, Pig: 85%, Rabbit: 77%, Yeast: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TNK1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 661 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TNK1

Target: TNK1 (Tyrosine Kinase, Non-Receptor, 1 (TNK1))

Andere Bezeichnung: TNK1 (TNK1 Produkte)

Synonyme: Kos1 antikoerper, Tnk1a antikoerper, Tnk1b antikoerper, Ack-like antikoerper, tyrosine kinase non receptor 1 antikoerper, tyrosine kinase, non-receptor, 1 antikoerper, TNK1 antikoerper, Tnk1 antikoerper

Hintergrund: The protein encoded by this gene belongs to the tyrosine protein kinase family. Tyrosine protein kinases are important regulators of intracellular signal transduction pathways, mediating cellular proliferation, survival, and development. This gene is highly expressed in fetal tissues and at lower levels in few adult tissues, thus may function in signaling pathways utilized broadly during fetal development, and more selectively in adult tissues. It plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: MGC46193
Protein Interaction Partner: HSP90AA1, UBC, PLCG1, TNK1, SFN,
Protein Size: 661

Molekulargewicht: 72 kDa

Gen-ID: 8711

NCBI Accession: NM_003985, NP_003976

UniProt: Q13470