TNK1 Antikörper (C-Term)

Produktnummer ABIN2790058

Der Kaninchen Polyklonal anti-TNK1 Antikörper wird verwendet zum Nachweis von TNK1 in Proben von Human, Meerschweinchen, Schwein, Kaninchen und Saccharomyces cerevisiae. Er wurde validiert für WB.

Kurzübersicht für TNK1 Antikörper (C-Term) (ABIN2790058)

Target: TNK1 (Tyrosine Kinase, Non-Receptor, 1 (TNK1))

Reaktivität: Human, Meerschweinchen, Schwein, Kaninchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TNK1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: TNK1 Antibody - C-terminal region

Sequenz: EIRQARAVPQ GPPGLPPRPP LSSSSPQPSQ PSRERLPWPK RKPPHNHPMG

Homologie: Guinea Pig: 83%, Human: 100%, Pig: 85%, Rabbit: 77%, Yeast: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TNK1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65151-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu TNK1

Target: TNK1 (Tyrosine Kinase, Non-Receptor, 1 (TNK1))

Andere Bezeichnung: TNK1

Hintergrund:

Background Information: The protein encoded by this gene belongs to the tyrosine protein kinase family. Tyrosine protein kinases are important regulators of intracellular signal transduction pathways, mediating cellular proliferation, survival, and development. This gene is highly expressed in fetal tissues and at lower levels in few adult tissues, thus may function in signaling pathways utilized broadly during fetal development, and more selectively in adult tissues. It plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: Tyrosine kinase, non-receptor, 1

Alternative Symbols: KOS1

Protein Name: Non-receptor tyrosine-protein kinase TNK1

Molekulargewicht: 72kDa

Gen-ID: 8711

NCBI Accession: NP_003976

UniProt: Q13470