C8orf4 Antikörper (N-Term)

Produktnummer ABIN2790028

Produktdetails anti-C8orf4 Antikörper

Target: C8orf4 (Chromosome 8 Open Reading Frame 4 (C8orf4))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Kaninchen, Rind (Kuh), Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C8orf4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TASRKKAVGN IFENTDQESL ERLFRNSGDK KAEERAKIIF AIDQDVEEKT

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against C8orf4. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human C8orf4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 106 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu C8orf4

Target: C8orf4 (Chromosome 8 Open Reading Frame 4 (C8orf4))

Andere Bezeichnung: C8orf4 (C8orf4 Produkte)

Synonyme: TC-1 antikoerper, TC1 antikoerper, 1110065B09Rik antikoerper, AW121743 antikoerper, AW321058 antikoerper, C8ORF4 antikoerper, transcriptional and immune response regulator antikoerper, chromosome 22 open reading frame, human C8orf4 antikoerper, TCIM antikoerper, C22H8ORF4 antikoerper, Tcim antikoerper

Hintergrund: This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies.
Alias Symbols: MGC22806, TC-1, TC1, hTC-1
Protein Interaction Partner: ELAVL1, UBC,
Protein Size: 106

Molekulargewicht: 12 kDa

Gen-ID: 56892

NCBI Accession: NM_020130, NP_064515

UniProt: Q9NR00