C8orf4 Antikörper (N-Term)

Produktnummer ABIN2790028

Produktdetails anti-C8orf4 Antikörper

Target: C8orf4 (Chromosome 8 Open Reading Frame 4 (C8orf4))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Rind (Kuh), Hund, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C8orf4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TASRKKAVGN IFENTDQESL ERLFRNSGDK KAEERAKIIF AIDQDVEEKT

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against C8orf4. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human C8orf4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 106 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu C8orf4

Target: C8orf4 (Chromosome 8 Open Reading Frame 4 (C8orf4))

Andere Bezeichnung: C8orf4 (C8orf4 Produkte)

Hintergrund: This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies.
Alias Symbols: MGC22806, TC-1, TC1, hTC-1
Protein Interaction Partner: ELAVL1, UBC,
Protein Size: 106

Molekulargewicht: 12 kDa

Gen-ID: 56892

NCBI Accession: NM_020130, NP_064515

UniProt: Q9NR00