CRYGA Antikörper (N-Term)

Produktnummer ABIN2790019

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CRYGA in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio).

Kurzübersicht für CRYGA Antikörper (N-Term) (ABIN2790019)

Target: CRYGA (Crystallin, gamma A (CRYGA))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRYGA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CRYGA Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: CRYGA Antibody - N-terminal region

Sequenz: SIRVDSGCWM LYERPNYQGH QYFLRRGKYP DYQHWMGLSD SVQSCRIIPH

Homologie: Cow: 79%, Dog: 79%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 79%, Rabbit: 79%, Rat: 79%, Zebrafish: 82%

Produktmerkmale: This is a rabbit polyclonal antibody against CRYGA. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human CRYGA

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65008-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu CRYGA

Target: CRYGA (Crystallin, gamma A (CRYGA))

Andere Bezeichnung: CRYGA

Hintergrund:

Background Information: Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families, beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation.

Alternative Symbols: CRYG1, CRYG5, CRY-g-A

Protein Name: Gamma-crystallin A

Molekulargewicht: 21kDa

Gen-ID: 1418

NCBI Accession: NP_055432

UniProt: P11844