EI24 Antikörper (N-Term)

Produktnummer ABIN2790002

Produktdetails anti-EI24 Antikörper

Target: EI24 (Etoposide Induced 2.4 (EI24))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EI24 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ICTISKLDAR IQQKREEQRR RRASSVLAQR RAQSIERKQE SEPRIVSRIF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 77%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against EI24. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 262 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu EI24

Target: EI24 (Etoposide Induced 2.4 (EI24))

Andere Bezeichnung: EI24 (EI24 Produkte)

Hintergrund: This gene has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The protein encoded by this gene contains six putative transmembrane domains and may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in two transcript variants encoding different isoforms.
Alias Symbols: PIG8, TP53I8
Protein Interaction Partner: UBC,
Protein Size: 262

Molekulargewicht: 30 kDa

Gen-ID: 9538

NCBI Accession: NM_001007277, NP_001007278

UniProt: O14681