IPO7 Antikörper (C-Term)
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- Target Alle IPO7 Antikörper anzeigen
- IPO7 (Importin 7 (IPO7))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Rind (Kuh), Ratte, Hund, Pferd, Meerschweinchen, Kaninchen, Schwein, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IPO7 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- NVIQKMICEY SEEVTPIAVE MTQHLAMTFN QVIQTGPDEE GSDDKAVTAM
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against IPO7. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product IPO7 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 1038 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- IPO7 (Importin 7 (IPO7))
- Andere Bezeichnung
- IPO7 (IPO7 Produkte)
- Synonyme
- fb33d09 antikoerper, wu:fb33d09 antikoerper, zgc:66425 antikoerper, zgc:76878 antikoerper, imp7 antikoerper, ranbp7 antikoerper, Imp7 antikoerper, RANBP7 antikoerper, A330055O14Rik antikoerper, C330016G14 antikoerper, Ranbp7 antikoerper, importin 7 antikoerper, importin 7 S homeolog antikoerper, importin-7 antikoerper, karyopherin antikoerper, ipo7 antikoerper, ipo7.S antikoerper, IPO7 antikoerper, CpipJ_CPIJ002096 antikoerper, PTRG_08544 antikoerper, SJAG_03693 antikoerper, NAEGRDRAFT_71372 antikoerper, VDBG_01971 antikoerper, MGYG_08162 antikoerper, Tsp_01943 antikoerper, Tsp_01946 antikoerper, Ipo7 antikoerper
- Hintergrund
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The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions.
Alias Symbols: FLJ14581, Imp7, MGC138673, RANBP7
Protein Interaction Partner: SUMO2, SUMO3, STAU1, RNF2, rev, TNPO1, KARS, HSPA1L, HARS, APEH, PFDN5, NFRKB, ELAC2, CAND1, TRMT112, HSPA4L, RNASEH2A, FBXO6, EGFR, SOX2, METTL18, UBC, CFTR, CA9, IGBP1, RAN, CDK2, FBXO25, SIRT7, RNF146, MYC, AIRE, USP49, RPL23A, RPS7, RPL5, KPNB1, SRP19
Protein Size: 1038 - Molekulargewicht
- 119 kDa
- Gen-ID
- 10527
- NCBI Accession
- NM_006391, NP_006382
- UniProt
- O95373
- Pathways
- Protein targeting to Nucleus
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