IPO7 Antikörper (C-Term)

Produktnummer ABIN2789995

Dieses Anti-IPO7-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von IPO7 in WB. Geeignet für Human, Maus, Rind (Kuh), Ratte, Hund, Pferd, Meerschweinchen, Kaninchen, Schwein und Zebrafisch (Danio rerio).

Kurzübersicht für IPO7 Antikörper (C-Term) (ABIN2789995)

Target: IPO7 (Importin 7 (IPO7))

Reaktivität: Human, Maus, Rind (Kuh), Ratte, Hund, Pferd, Meerschweinchen, Kaninchen, Schwein, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IPO7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IPO7 Antikörper

Bindungsspezifität: C-Term

Sequenz: NVIQKMICEY SEEVTPIAVE MTQHLAMTFN QVIQTGPDEE GSDDKAVTAM

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against IPO7. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1038 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu IPO7

Target: IPO7 (Importin 7 (IPO7))

Andere Bezeichnung: IPO7

Hintergrund: The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions.
Alias Symbols: FLJ14581, Imp7, MGC138673, RANBP7
Protein Interaction Partner: SUMO2, SUMO3, STAU1, RNF2, rev, TNPO1, KARS, HSPA1L, HARS, APEH, PFDN5, NFRKB, ELAC2, CAND1, TRMT112, HSPA4L, RNASEH2A, FBXO6, EGFR, SOX2, METTL18, UBC, CFTR, CA9, IGBP1, RAN, CDK2, FBXO25, SIRT7, RNF146, MYC, AIRE, USP49, RPL23A, RPS7, RPL5, KPNB1, SRP19
Protein Size: 1038

Molekulargewicht: 119 kDa

Gen-ID: 10527

NCBI Accession: NM_006391, NP_006382

UniProt: O95373

Pathways: Protein targeting to Nucleus