ATL1 Antikörper (C-Term)

Produktnummer ABIN2789990

Der Kaninchen Polyklonal anti-ATL1 Antikörper wird verwendet zum Nachweis von ATL1 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für ATL1 Antikörper (C-Term) (ABIN2789990)

Target: ATL1 (Atlastin GTPase 1 (ATL1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ATL1 Antikörper

Bindungsspezifität: C-Term

Sequenz: DQVAAALWDQ GSTNEALYKL YSAAATHRHL YHQAFPTPKS ESTEQSEKKK

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 77%, Pig: 100%, Rabbit: 92%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against SPG3A. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human ATL1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ATL1

Target: ATL1 (Atlastin GTPase 1 (ATL1))

Andere Bezeichnung: SPG3A

Hintergrund: The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: FSP1, GBP3, SPG3, HSN1D, SPG3A, AD-FSP, atlastin1
Protein Size: 475

Molekulargewicht: 52 kDa

Gen-ID: 51062

NCBI Accession: NM_001127713, NP_001121185

UniProt: Q8WXF7