ATL1 Antikörper (C-Term)

Produktnummer ABIN2789990

Produktdetails anti-ATL1 Antikörper

Target: ATL1 (Atlastin GTPase 1 (ATL1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: DQVAAALWDQ GSTNEALYKL YSAAATHRHL YHQAFPTPKS ESTEQSEKKK

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 77%, Pig: 100%, Rabbit: 92%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against SPG3A. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human ATL1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ATL1

Target: ATL1 (Atlastin GTPase 1 (ATL1))

Andere Bezeichnung: SPG3A (ATL1 Produkte)

Hintergrund: The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: FSP1, GBP3, SPG3, HSN1D, SPG3A, AD-FSP, atlastin1
Protein Size: 475

Molekulargewicht: 52 kDa

Gen-ID: 51062

NCBI Accession: NM_001127713, NP_001121185

UniProt: Q8WXF7