Plakophilin 4 Antikörper (N-Term)

Produktnummer ABIN2789970

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Plakophilin 4 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Schwein, Kaninchen, Hund, Meerschweinchen und Pferd.

Kurzübersicht für Plakophilin 4 Antikörper (N-Term) (ABIN2789970)

Target: Plakophilin 4 (PKP4)

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Kaninchen, Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Plakophilin 4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Plakophilin 4 Antikörper

Bindungsspezifität: N-Term

Sequenz: MPAPEQASLV EEGQPQTRQE AASTGPGMEP ETTATTILAS VKEQELQFQR

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 93%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against PKP4. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1149 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Plakophilin 4

Target: Plakophilin 4 (PKP4)

Andere Bezeichnung: PKP4

Hintergrund: Armadillo-like proteins are characterized by a series of armadillo repeats, first defined in the Drosophila 'armadillo' gene product, that are typically 42 to 45 amino acids in length. These proteins can be divided into subfamilies based on their number of repeats, their overall sequence similarity, and the dispersion of the repeats throughout their sequences. Members of the p120(ctn)/plakophilin subfamily of Armadillo-like proteins, including CTNND1, CTNND2, PKP1, PKP2, PKP4, and ARVCF. PKP4 may be a component of desmosomal plaque and other adhesion plaques and is thought to be involved in regulating junctional plaque organization and cadherin function. Multiple transcript variants have been found for this gene, but the full-length nature of only two of them have been described so far.
Alias Symbols: FLJ31261, FLJ42243, p0071
Protein Interaction Partner: ATPAF2, LZTS2, UBC, GOLGA2, TRIM23, SAV1, LATS2, LATS1, PAXIP1, ATP6V1B1, LNX1, OSGEP, MINK1, PDZD2, ERBB2IP, GABARAP, CDH5, DSC3, PGAM1, DSP, PSEN1, CDH2, CDH1,
Protein Size: 1149

Molekulargewicht: 127 kDa

Gen-ID: 8502

NCBI Accession: NM_001005476, NP_001005476

Pathways: Cell-Cell Junction Organization