PACS1 Antikörper (C-Term)

Produktnummer ABIN2789968

Der Kaninchen Polyklonal Anti-PACS1-Antikörper wurde für WB validiert. Er ist geeignet, PACS1 in Proben von Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Meerschweinchen, Kaninchen und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für PACS1 Antikörper (C-Term) (ABIN2789968)

Target: PACS1 (phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PACS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PACS1 Antikörper

Bindungsspezifität: C-Term

Sequenz: FLSKKPREKE VDSKSQVIEG ISRLICSAKQ QQTMLRVSID GVEWSDIKFF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against PACS1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 366 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PACS1

Target: PACS1 (phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))

Andere Bezeichnung: PACS1

Hintergrund: This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance.
Alias Symbols: -
Protein Interaction Partner: UBC, GGA3, CSNK2A1, FGFR1OP, PPP2CA, VAMP4, CLCN7, PPP2CB, PKD2, JUN, IGF2R, FURIN, TRPV4, nef,
Protein Size: 366

Molekulargewicht: 42 kDa

Gen-ID: 55690

NCBI Accession: NM_018026

UniProt: Q6VY07