TXNRD3 Antikörper (Middle Region)

Produktnummer ABIN2789949

Der Kaninchen Polyklonal Anti-TXNRD3-Antikörper wurde für WB validiert. Er ist geeignet, TXNRD3 in Proben von Human, Maus, Kaninchen, Hund, Meerschweinchen, Pferd, Schwein, Ratte und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für TXNRD3 Antikörper (Middle Region) (ABIN2789949)

Target: TXNRD3 (Thioredoxin Reductase 3 (TXNRD3))

Reaktivität: Human, Maus, Kaninchen, Hund, Meerschweinchen, Pferd, Schwein, Ratte, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TXNRD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TXNRD3 Antikörper

Bindungsspezifität: Middle Region

Sequenz: NHISSLNWGY RLSLREKAVA YVNSYGEFVE HHKIKATNKK GQETYYTAAQ

Homologie: Dog: 86%, Guinea Pig: 77%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 85%, Rat: 79%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against TXNRD3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 607 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TXNRD3

Target: TXNRD3 (Thioredoxin Reductase 3 (TXNRD3))

Andere Bezeichnung: TXNRD3

Hintergrund: This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein catalyzes the reduction of thioredoxin, and is implicated in the defense against oxidative stress. It contains a selenocysteine (Sec) residue (which is essential for catalytic activity), encoded by a UGA codon, at the penultimate C-terminal position. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: TGR, TR2, TRXR3
Protein Interaction Partner: UBC,
Protein Size: 607

Molekulargewicht: 66 kDa

Gen-ID: 114112

NCBI Accession: NM_001173513, NP_001166984

UniProt: Q86VQ6

Pathways: Cell RedoxHomeostasis