SUCLA2 Antikörper (N-Term)
Kurzübersicht für SUCLA2 Antikörper (N-Term) (ABIN2789920)
Target
Alle SUCLA2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- LKGGVKIVFS PEEAKAVSSQ MIGKKLFTKQ TGEKGRICNQ VLVCERKYPR
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 91%, Zebrafish: 93%
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Produktmerkmale
- This is a rabbit polyclonal antibody against SUCLA2. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 463 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SUCLA2 (Succinate-CoA Ligase, ADP-Forming, beta Subunit (SUCLA2))
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Andere Bezeichnung
- SUCLA2
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Hintergrund
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Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6.
Alias Symbols: A-BETA, SCS-betaA, MTDPS5
Protein Interaction Partner: FAM9B, CMTM5, AGTRAP, ARL6IP1, SUMO2, UBC, gag-pol, MRPL12, RBM4, OXCT1, IDH3A, AGFG1, S100A16, NADK2, HPDL, NIT2, SEC22B, GRHPR, SUCLG1, SDHA, RRM1, AGO4, ICT1, PSMD14, ALAS2,
Protein Size: 463 -
Molekulargewicht
- 45 kDa
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Gen-ID
- 8803
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NCBI Accession
- NM_003850, NP_003841
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UniProt
- Q9P2R7
Target
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