SUCLA2 Antikörper (C-Term)

Produktnummer ABIN2789919

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SUCLA2 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Pferd, Schwein, Hund, Meerschweinchen und Kaninchen.

Kurzübersicht für SUCLA2 Antikörper (C-Term) (ABIN2789919)

Target: SUCLA2 (Succinate-CoA Ligase, ADP-Forming, beta Subunit (SUCLA2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Schwein, Hund, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SUCLA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SUCLA2 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: SUCLA2 Antibody - C-terminal region

Sequenz: FDLQDWTQED ERDKDAAKAN LNYIGLDGNI GCLVNGAGLA MATMDIIKLH

Homologie: Cow: 100%, Dog: 86%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against SUCLA2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64675-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu SUCLA2

Target: SUCLA2 (Succinate-CoA Ligase, ADP-Forming, beta Subunit (SUCLA2))

Andere Bezeichnung: SUCLA2

Hintergrund:

Targeted Subunit: beta, mitochondrial

Background Information: Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6.

Gene Name: Succinate-CoA ligase, ADP-forming, beta subunit

Alternative Symbols: A-SCS, A-BETA, MTDPS5, LINC00444, SCS-betaA

Protein Name: Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial

Molekulargewicht: 45kDa

Gen-ID: 8803

NCBI Accession: NP_003841

UniProt: Q9P2R7