GPS2 Antikörper (N-Term)

Produktnummer ABIN2789898

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GPS2 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Saccharomyces cerevisiae und Zebrafisch (Danio rerio).

Kurzübersicht für GPS2 Antikörper (N-Term) (ABIN2789898)

Target: GPS2 (G Protein Pathway Suppressor 2 (GPS2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GPS2 Antikörper

Bindungsspezifität: N-Term

Sequenz: LKKVLHEEEK RRRKEQSDLT TLTSAAYQQS LTVHTGTHLL NMQGSPGGHN

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 91%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against Gps2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of mouse GPS2

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GPS2

Target: GPS2 (G Protein Pathway Suppressor 2 (GPS2))

Andere Bezeichnung: Gps2

Hintergrund: This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.
Alias Symbols: AMF-1
Protein Size: 327

Molekulargewicht: 37 kDa

Gen-ID: 2874

NCBI Accession: NM_004489, NP_004480

UniProt: Q13227