DMGDH Antikörper (Middle Region)

Produktnummer ABIN2789895

Der Kaninchen Polyklonal anti-DMGDH Antikörper wird verwendet zum Nachweis von DMGDH in Proben von Human, Maus, Ratte, Schwein, Pferd, Kaninchen, Zebrafisch (Danio rerio), Rind (Kuh), Hund und Meerschweinchen. Er wurde validiert für WB.

Kurzübersicht für DMGDH Antikörper (Middle Region) (ABIN2789895)

Target: DMGDH (Dimethylglycine Dehydrogenase (DMGDH))

Reaktivität: Human, Maus, Ratte, Schwein, Pferd, Kaninchen, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DMGDH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DMGDH Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: DMGDH Antibody - middle region

Sequenz: SELHDLRWIE EAAFRGGYDV EIQNITDEFG VLGVAGPYAR RVLQKLTSE

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against Dmgdh. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of mouse DMGDH

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64604-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu DMGDH

Target: DMGDH (Dimethylglycine Dehydrogenase (DMGDH))

Andere Bezeichnung: DMGDH

Hintergrund:

Background Information: This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants.

Gene Name: dimethylglycine dehydrogenase

Alternative Symbols: DMGDHD, ME2GLYDH

Protein Name: dimethylglycine dehydrogenase, mitochondrial

Molekulargewicht: 93kDa

Gen-ID: 29958

NCBI Accession: NP_037523

UniProt: Q9UI17