DMGDH Antikörper (Middle Region)

Produktnummer ABIN2789895

Produktdetails anti-DMGDH Antikörper

Target: DMGDH (Dimethylglycine Dehydrogenase (DMGDH))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Schwein, Pferd, Kaninchen, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DMGDH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SELHDLRWIE EAAFRGGYDV EIQNITDEFG VLGVAGPYAR RVLQKLTSE

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against Dmgdh. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of mouse DMGDH

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DMGDH

Target: DMGDH (Dimethylglycine Dehydrogenase (DMGDH))

Andere Bezeichnung: Dmgdh (DMGDH Produkte)

Synonyme: MGC132281 antikoerper, DMGDHD antikoerper, ME2GLYDH antikoerper, Me2GlyDH antikoerper, 1200014D15Rik antikoerper, AI787269 antikoerper, dimethylglycine dehydrogenase antikoerper, dimethylglycine dehydrogenase L homeolog antikoerper, D-amino-acid oxidase antikoerper, Dimethylglycine dehydrogenase antikoerper, glycine cleavage system protein T antikoerper, dimethylglycine dehydrogenase precursor antikoerper, DMGDH antikoerper, dmgdh.L antikoerper, dmgdh antikoerper, SAR11_1253 antikoerper, EAMY_RS27375 antikoerper, EAMY_RS33570 antikoerper, VDBG_06516 antikoerper, Sinme_2570 antikoerper, HALXA_RS03495 antikoerper, Dmgdh antikoerper

Hintergrund: This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants.
Alias Symbols: DMGDHD, ME2GLYDH
Protein Size: 869

Molekulargewicht: 93 kDa

Gen-ID: 29958

NCBI Accession: NM_013391, NP_037523

UniProt: Q9UI17