DMGDH Antikörper (C-Term)

Produktnummer ABIN2789894

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch DMGDH in WB. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Schwein und Pferd.

Kurzübersicht für DMGDH Antikörper (C-Term) (ABIN2789894)

Target: DMGDH (Dimethylglycine Dehydrogenase (DMGDH))

Reaktivität: Human, Ratte, Schwein, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DMGDH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DMGDH Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: DMGDH Antibody - C-terminal region

Sequenz: YVPVQLSEVG QQVEVELLGK NYPAVIIQEP LVLTEPTRNR LQKKGGKDKT

Homologie: Horse: 92%, Human: 100%, Pig: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against DMGDH. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64603-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu DMGDH

Target: DMGDH (Dimethylglycine Dehydrogenase (DMGDH))

Andere Bezeichnung: DMGDH

Hintergrund:

Background Information: This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum.

Gene Name: Dimethylglycine dehydrogenase

Alternative Symbols: DMGDHD, ME2GLYDH

Protein Name: Dimethylglycine dehydrogenase, mitochondrial

Molekulargewicht: 91kDa

Gen-ID: 29958

NCBI Accession: NP_037523

UniProt: Q9UI17