TP53I3 Antikörper (C-Term)

Produktnummer ABIN2789865

Dieses Anti-TP53I3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TP53I3 in WB. Geeignet für Human, Ratte, Rind (Kuh), Hund, Pferd, Schwein und Kaninchen.

Kurzübersicht für TP53I3 Antikörper (C-Term) (ABIN2789865)

Target: TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))

Reaktivität: Human, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TP53I3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TP53I3 Antikörper

Bindungsspezifität: C-Term

Sequenz: SKLLFKRGSL ITSLLRSRDN KYKQMLVNAF TEQILPHFST EGPQRLLPVL

Homologie: Cow: 86%, Dog: 85%, Horse: 83%, Human: 100%, Pig: 93%, Rabbit: 86%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against TP53I3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human TP53I3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 243 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TP53I3

Target: TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))

Andere Bezeichnung: TP53I3

Hintergrund: The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer.
Alias Symbols: PIG3
Protein Interaction Partner: TLDC1, PLK1, UBC, TP53BP1, H2AFX, EEF1G, UBR1, FUNDC2, UNC119, TP53,
Protein Size: 243

Molekulargewicht: 26 kDa

Gen-ID: 9540

NCBI Accession: NM_001206802

UniProt: B4DMQ7

Pathways: p53 Signalweg