NCK1 Antikörper (N-Term)

Produktnummer ABIN2789859

Der Kaninchen Polyklonal Anti-NCK1-Antikörper wurde für WB validiert. Er ist geeignet, NCK1 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Schaf und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für NCK1 Antikörper (N-Term) (ABIN2789859)

Target: NCK1 (NCK Adaptor Protein 1 (NCK1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Schaf, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NCK1 Antikörper

Bindungsspezifität: N-Term

Sequenz: PSNYVERKNS ARKASIVKNL KDTLGIGKVK RKPSVPDSAS PADDSFVDPG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against NCK1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 377 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NCK1

Target: NCK1 (NCK Adaptor Protein 1 (NCK1))

Andere Bezeichnung: NCK1

Hintergrund: The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found.
Alias Symbols: MGC12668, NCK, NCKalpha, nck-1
Protein Interaction Partner: UBC, CBL, SYNPO, WAS, Dok1, HSPA5, Mbp, SHANK3, KIAA1522, Caskin1, LPHN2, ADAM15, TUBA1A, ERBB3, EGFR, PHC2, FGFR1, MAP4K1, BCAR1, nef, ABI1, PAK1, DNM1, ABL1, TNK2, FASLG, UBASH3B, SYK, PIK3R1, LCP2, INPP5D, GRB2, KHDRBS1, UBA52, RASA1, NCKAP5, TNIK, BRK
Protein Size: 377

Molekulargewicht: 42 kDa

Gen-ID: 4690

NCBI Accession: NM_006153, NP_006144

UniProt: P16333

Pathways: T-Zell Rezeptor Signalweg, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals