DNAJA3 Antikörper (C-Term)

Produktnummer ABIN2789841

Der Kaninchen Polyklonal Anti-DNAJA3-Antikörper wurde für WB validiert. Er ist geeignet, DNAJA3 in Proben von Human, Maus, Ratte, Meerschweinchen und Pferd zu detektieren.

Kurzübersicht für DNAJA3 Antikörper (C-Term) (ABIN2789841)

Target: DNAJA3 (DnaJ (Hsp40) Homolog, Subfamily A, Member 3 (DNAJA3))

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DNAJA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DNAJA3 Antikörper

Bindungsspezifität: C-Term

Sequenz: ETDVEGTVNG VTLTSSGGST MDSSAGSKAR REAGEDEEGF LSKLKKMFTS

Homologie: Guinea Pig: 86%, Horse: 85%, Human: 100%, Mouse: 92%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against DNAJA3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 480 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DNAJA3

Target: DNAJA3 (DnaJ (Hsp40) Homolog, Subfamily A, Member 3 (DNAJA3))

Andere Bezeichnung: DNAJA3

Hintergrund: This gene encodes a member of the DNAJ/Hsp40 protein family. DNAJ/Hsp40 proteins stimulate the ATPase activity of Hsp70 chaperones and play critical roles in protein folding, degradation, and multimeric complex assembly. The encoded protein is localized to mitochondria and mediates several cellular processes including proliferation, survival and apoptotic signal transduction. The encoded protein also plays a critical role in tumor suppression through interactions with oncogenic proteins including ErbB2 and the p53 tumor suppressor protein.
Alias Symbols: FLJ45758, TID1, hTid-1
Protein Interaction Partner: HUWE1, STK16, TCF19, FOSL2, PCSK9, ALS2CR11, FRMD6, FAM214B, MYO15B, GCC1, NOC4L, OSGIN1, INPP5J, IRS4, UBC, KDM1A, CARM1, PRMT6, LATS2, EGFR, HSP90AA1, HSPA1A, HDAC11, NOS2, SMAD9, RPS18, MYO1C, CLTC, NDUFS7, UQCRQ, SCFD1, CRK, HSPA9, GFI1B, COIL, USP7,
Protein Size: 480

Molekulargewicht: 52 kDa

Gen-ID: 9093

NCBI Accession: NM_005147, NP_005138

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity