GPR68 Antikörper (Middle Region)

Produktnummer ABIN2789838

Produktdetails anti-GPR68 Antikörper

Target: GPR68 (G Protein-Coupled Receptor 68 (GPR68))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Pferd, Kaninchen, Schwein, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPR68 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SIYFLMHEEV IEDENQHRVC FEHYPIQAWQ RAINYYRFLV GFLFPICLLL

Homologie: Dog: 79%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 79%, Rabbit: 79%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against GPR68. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human GPR68

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 365 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GPR68

Target: GPR68 (G Protein-Coupled Receptor 68 (GPR68))

Andere Bezeichnung: GPR68 (GPR68 Produkte)

Synonyme: GPR68 antikoerper, GPR12A antikoerper, OGR1 antikoerper, BB131428 antikoerper, Ogr1 antikoerper, G protein-coupled receptor 68 antikoerper, GPR68 antikoerper, LOC100348269 antikoerper, Gpr68 antikoerper

Hintergrund: Proton-sensing receptor is involved in pH homeostasis. GPR68 may represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. GPR68 mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca2+ mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer.
Alias Symbols: MGC111379, MGC156983, OGR1, GPR12A
Protein Size: 365

Molekulargewicht: 41 kDa

Gen-ID: 8111

NCBI Accession: NM_003485, NP_003476

UniProt: Q15743