GPR68 Antikörper (Middle Region)

Produktnummer ABIN2789838

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch GPR68 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Pferd, Kaninchen, Hund und Schwein.

Kurzübersicht für GPR68 Antikörper (Middle Region) (ABIN2789838)

Target: GPR68 (G Protein-Coupled Receptor 68 (GPR68))

Reaktivität: Human, Maus, Ratte, Pferd, Kaninchen, Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPR68 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GPR68 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: GPR68 Antibody - middle region

Sequenz: SIYFLMHEEV IEDENQHRVC FEHYPIQAWQ RAINYYRFLV GFLFPICLLL

Homologie: Dog: 79%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 79%, Rabbit: 79%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against GPR68. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human GPR68

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64436-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu GPR68

Target: GPR68 (G Protein-Coupled Receptor 68 (GPR68))

Andere Bezeichnung: GPR68

Hintergrund:

Background Information: Proton-sensing receptor is involved in pH homeostasis. GPR68 may represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. GPR68 mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca2+ mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer.

Gene Name: G protein-coupled receptor 68

Alternative Symbols: OGR1, AI2A6, GPR12A

Protein Name: Ovarian cancer G-protein coupled receptor 1

Molekulargewicht: 41kDa

Gen-ID: 8111

NCBI Accession: NP_003476

UniProt: Q15743