AQR Antikörper (C-Term)

Produktnummer ABIN2789836

Produktdetails anti-AQR Antikörper

Target: AQR (Aquarius Homolog (AQR))

Bindungsspezifität: C-Term

Reaktivität: Human, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AQR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: DTTPSETGAT STPEAIPALS ETTPTVVGAV SAPAEANTPQ DATSAPEETK

Homologie: Horse: 79%, Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against AQR. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human AQR

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1485 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu AQR

Target: AQR (Aquarius Homolog (AQR))

Andere Bezeichnung: AQR (AQR Produkte)

Hintergrund: AQR is an intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. AQR plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. AQR may act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.
Alias Symbols: DKFZp686B23123, IBP160, KIAA0560, fSAP164
Protein Interaction Partner: UBC, LGR4, SUZ12, RNF2, BMI1, ZNF830, WDR83, WDR77, RBM22, PQBP1, RBM4, EIF4A3, MAGOH, SIRT7, HNRNPA1, Prpf8, Cdc5l, Snw1, USP28,
Protein Size: 1485

Molekulargewicht: 171 kDa

Gen-ID: 9716

NCBI Accession: NM_014691, NP_055506

UniProt: O60306