Deoxyguanosine Kinase Antikörper (C-Term)

Produktnummer ABIN2789830

Der Kaninchen Polyklonal anti-Deoxyguanosine Kinase Antikörper (ABIN2789830) detektiert spezifisch Deoxyguanosine Kinase in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein und Kaninchen.

Kurzübersicht für Deoxyguanosine Kinase Antikörper (C-Term) (ABIN2789830)

Target: Deoxyguanosine Kinase (DGUOK)

Reaktivität: Human, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Deoxyguanosine Kinase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Deoxyguanosine Kinase Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: DGUOK Antibody - C-terminal region

Sequenz: EQLHGQHEAW LIHKTTKLHF EALMNIPVLV LDVNDDFSEE VTKQEDLMRE

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Pig: 86%, Rabbit: 86%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against DGUOK. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human DGUOK

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64409-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Deoxyguanosine Kinase

Target: Deoxyguanosine Kinase (DGUOK)

Andere Bezeichnung: DGUOK

Hintergrund:

Background Information: In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene.

Alternative Symbols: dGK, NCPH, PEOB4, MTDPS3

Protein Name: Deoxyguanosine kinase, mitochondrial

Molekulargewicht: 28kDa

Gen-ID: 1716

NCBI Accession: NP_550438

UniProt: Q16854

Pathways: Ribonucleoside Biosynthetic Process