Deoxyguanosine Kinase Antikörper (C-Term)

Produktnummer ABIN2789830

Produktdetails anti-Deoxyguanosine Kinase Antikörper

Target: Deoxyguanosine Kinase (DGUOK)

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Deoxyguanosine Kinase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EQLHGQHEAW LIHKTTKLHF EALMNIPVLV LDVNDDFSEE VTKQEDLMRE

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Pig: 86%, Rabbit: 86%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against DGUOK. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human DGUOK

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 277 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Deoxyguanosine Kinase

Target: Deoxyguanosine Kinase (DGUOK)

Andere Bezeichnung: DGUOK (DGUOK Produkte)

Hintergrund: In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene.
Alias Symbols: dGK
Protein Interaction Partner: UBC, PXN, LIG4, APP, DGUOK,
Protein Size: 277

Molekulargewicht: 28 kDa

Gen-ID: 1716

NCBI Accession: NM_080916, NP_550438

UniProt: Q16854

Pathways: Ribonucleoside Biosynthetic Process