CDC14A Antikörper (C-Term)
Kurzübersicht für CDC14A Antikörper (C-Term) (ABIN2789804)
Target
Alle CDC14A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- DDDVEMKNGI TQGDKLRALK SQRQPRTSPS CAFRSDDTKG HPRAVSQPFR
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Homologie
- Cow: 100%, Dog: 87%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%
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Produktmerkmale
- This is a rabbit polyclonal antibody against CDC14A. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 594 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CDC14A (CDC14 Cell Division Cycle 14 Homolog A (CDC14A))
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Andere Bezeichnung
- CDC14A
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Hintergrund
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The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of this gene results in several transcript variants encoding distinct isoforms.
Alias Symbols: cdc14, hCDC14
Protein Interaction Partner: CHRM1, CDC6, CDC25B, POLR2A, NPM1, FZR1, TP53, CCNB1, KIF20A, BRAP,
Protein Size: 594 -
Molekulargewicht
- 66 kDa
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Gen-ID
- 8556
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NCBI Accession
- NM_003672, NP_003663
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UniProt
- Q9UNH5
Target
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