ORC5 Antikörper (C-Term)

Produktnummer ABIN2789793

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ORC5 in WB. Er zeigt eine Reaktivität gegenüber Maus, Human, Ratte, Rind (Kuh), Hund, Pferd, Schwein und Kaninchen.

Kurzübersicht für ORC5 Antikörper (C-Term) (ABIN2789793)

Target: ORC5 (Origin Recognition Complex, Subunit 5 (ORC5))

Reaktivität: Maus, Human, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ORC5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ORC5 Antikörper

Bindungsspezifität: C-Term

Sequenz: TRKLWRNIEP HLKKAMQTVY LREISSSQWE KLQKDDTDPG QLKGIRGSIE

Homologie: Cow: 100%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ORC5. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 324 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ORC5

Target: ORC5 (Origin Recognition Complex, Subunit 5 (ORC5))

Andere Bezeichnung: ORC5

Hintergrund: The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Alias Symbols: ORC5, ORC5P, ORC5T
Protein Interaction Partner: NIF3L1, ORC4, ORC2, ORC1, NONO, MCM5, MCM3, MCM2, LAMB2, KRT18, CDC6, CDC5L, DMRTA1, SIPA1L2, UBQLN4, TXNDC11, PPP1CA, ORC3, STAB1, CALCOCO2, TAX1BP1, CDC45, CDC7, UBC, LRWD1, DGKA, UBD, tat, MCM7, ORC6, DBF4, RPA2, ORC5, MCM4,
Protein Size: 324

Molekulargewicht: 37 kDa

Gen-ID: 5001

NCBI Accession: NM_181747, NP_859531

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA