Der Kaninchen Polyklonal anti-PSTPIP1 Antikörper wird verwendet zum Nachweis von PSTPIP1 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen und Zebrafisch (Danio rerio). Er wurde validiert für WB.
PSTPIP1
Reaktivität: Human
WB, ELISA, FACS
Wirt: Kaninchen
Polyclonal
PE
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeat freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target
PSTPIP1
(Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1))
Andere Bezeichnung
PSTPIP1
Hintergrund
The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome. Protein Interaction Partner: RTP5, TRAF3IP3, FBXL18, SH2D4A, PCDHB14, UBE2W, FAM90A1, PRPF31, LSM4, BUB3, ZNF175, TULP3, SPG7, SDCBP, MVP, WASL, DNM2, MED28, SHBG, KHDRBS1, WAS, TUBB, WIPF1, HSPA1A, CARS, ACTB, PTPN18, WASF2, WASF1, CD2AP, PTPN12, MEFV, ABL1, CD2, FASLG, BZW2, RPL36, Protein Size: 397