PSTPIP1 Antikörper (N-Term)
Kurzübersicht für PSTPIP1 Antikörper (N-Term) (ABIN2499291)
Target
Alle PSTPIP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- LLRQRAQAEE RYGKELVQIA RKAGGQTEIN SLRASFDSLK QQMENVGSSH
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 92%
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Produktmerkmale
- This is a rabbit polyclonal antibody against PSTPIP1. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human PSTPIP1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeat freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PSTPIP1 (Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1))
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Andere Bezeichnung
- PSTPIP1
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Hintergrund
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The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome.
Protein Interaction Partner: RTP5, TRAF3IP3, FBXL18, SH2D4A, PCDHB14, UBE2W, FAM90A1, PRPF31, LSM4, BUB3, ZNF175, TULP3, SPG7, SDCBP, MVP, WASL, DNM2, MED28, SHBG, KHDRBS1, WAS, TUBB, WIPF1, HSPA1A, CARS, ACTB, PTPN18, WASF2, WASF1, CD2AP, PTPN12, MEFV, ABL1, CD2, FASLG, BZW2, RPL36,
Protein Size: 397 -
Molekulargewicht
- 43 kDa
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Gen-ID
- 9051
Target
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