BANF1 Antikörper (Middle Region)
Kurzübersicht für BANF1 Antikörper (Middle Region) (ABIN2789779)
Target
Alle BANF1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- FDKAYVVLGQ FLVLKKDEDL FREWLKDTCG ANAKQSRDCF GCLREWCDAF
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Homologie
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 91%
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Produktmerkmale
- This is a rabbit polyclonal antibody against BANF1. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of Human BANF1
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 89 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- BANF1 (Barrier To Autointegration Factor 1 (BANF1))
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Andere Bezeichnung
- BANF1
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Hintergrund
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The protein encoded by this gene was first identified by its ability to protect retroviruses from intramolecular integration and therefore promote intermolecular integration into the host cell genome. The protein forms a homodimer which localizes to both the nucleus and cytoplasm and is specifically associated with chromosomes during mitosis. This protein binds to double stranded DNA in a non-specific manner and also binds to LEM-domain containing proteins of the nuclear envelope. This protein is thought to facilitate nuclear reassembly by binding with both DNA and inner nuclear membrane proteins and thereby recruit chromatin to the nuclear periphery. Alternative splicing results in multiple transcript variants encoding the same protein.
Alias Symbols: BAF, BCRP1, D14S1460, MGC111161
Protein Interaction Partner: UBC, ERBB2IP, HIST1H3B, EMD, FBL, CRX, ATP6V1B1, LUC7L3, TMPO, EHMT2, SET, EVC2, ZNF428, LMNB2, DPY30, SMOC2, APTX, ACIN1, CBX3, PSIP1, CBX1, SUB1, CD2BP2, MDC1, BCL7C, MTA2, BANF1, CUL4A, CHAF1B, XPC, TUFM, SNRPD3, SMARCE1, SMARCC2, SMARCA2, TRA2B, DPF2,
Protein Size: 89 -
Molekulargewicht
- 10 kDa
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Gen-ID
- 8815
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NCBI Accession
- NM_003860, NP_003851
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UniProt
- O75531
Target
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