CDK2AP1 Antikörper (C-Term)
Kurzübersicht für CDK2AP1 Antikörper (C-Term) (ABIN2789771)
Target
Alle CDK2AP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- LLAIIEELGK EIRPTYAGSK SAMERLKRGI IHARGLVREC LAETERNARS
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
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Produktmerkmale
- This is a rabbit polyclonal antibody against CDK2AP1. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human CDK2AP1
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 115 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CDK2AP1 (Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1))
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Andere Bezeichnung
- CDK2AP1
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Hintergrund
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The protein encoded by this gene is a specific CDK2-associated protein, which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggested the regulatory role in DNA replication during S phase of the cell cycle. A similar gene in hamster was isolated from, and functions as a growth suppressor of normal keratinocytes.
Alias Symbols: DOC1, DORC1, ST19, doc-1, p12DOC-1
Protein Interaction Partner: MRFAP1L1, CCDC136, HDAC2, HDAC1, ZNF420, MTA3, VCP, CDK2AP2, Cebpb, HHV8GK18_gp81, ELAVL1, MBD3, MBD2, RBBP7, RBBP4, SRRM2, POLA1, CDK2, IGHA2, IGHA1, AMY1A,
Protein Size: 115 -
Molekulargewicht
- 12 kDa
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Gen-ID
- 8099
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NCBI Accession
- NM_004642, NP_004633
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UniProt
- O14519
Target
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