Myotilin Antikörper (C-Term)

Produktnummer ABIN2789737

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch Myotilin in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd und Kaninchen.

Kurzübersicht für Myotilin Antikörper (C-Term) (ABIN2789737)

Target: Myotilin (MYOT)

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Myotilin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Myotilin Antikörper

Bindungsspezifität: C-Term

Sequenz: RNNEMVQFNT DRISLYQDNT GRVTLLIKDV NKKDAGWYTV SAVNEAGVTT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MYOT. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 498 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Myotilin

Target: Myotilin (MYOT)

Andere Bezeichnung: MYOT

Hintergrund: This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Alias Symbols: LGMD1, LGMD1A, TTID
Protein Interaction Partner: NME7, TRIM63, TRIM55, GPRASP2, TFG, AXIN1, APP, LRP12, MYOT, FLNA, ACTN1, FLNC, ST7,
Protein Size: 498

Molekulargewicht: 55 kDa

Gen-ID: 9499

NCBI Accession: NM_006790, NP_006781

UniProt: Q9UBF9