Melatonin Receptor 1B Antikörper (N-Term)

Produktnummer ABIN2789720

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Melatonin Receptor 1B in WB. Er zeigt eine Reaktivität gegenüber Human, Schwein und Kaninchen und wurde in 1 Publikation erwähnt.

Kurzübersicht für Melatonin Receptor 1B Antikörper (N-Term) (ABIN2789720)

Target: Melatonin Receptor 1B (MTNR1B)

Reaktivität: Human, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Melatonin Receptor 1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Melatonin Receptor 1B Antikörper

Bindungsspezifität: N-Term

Sequenz: SFANCCEAGG WAVRPGWSGA GSARPSRTPR PPWVAPALSA VLIVTTAVDV

Homologie: Human: 100%, Pig: 79%, Rabbit: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against MTNR1B. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 362 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Melatonin Receptor 1B Antikörper (ABIN2789720)

Santoro, Mori, Marani, Grasso, Cambria, Blandino, Muti, Strano: "Blockage of melatonin receptors impairs p53-mediated prevention of DNA damage accumulation." in: Carcinogenesis, Vol. 34, Issue 5, pp. 1051-61, (2013) (PubMed).

Details zu Melatonin Receptor 1B

Target: Melatonin Receptor 1B (MTNR1B)

Andere Bezeichnung: MTNR1B

Hintergrund: This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin.
Alias Symbols: FGQTL2, MEL-1B-R, MT2
Protein Interaction Partner: GNAI1, GPR50, ITM2C, HNRNPA0, GNB4, PPM1G, PI4KA, PDIA6, VPS35, IRS4, COPA, CTNND1, MTNR1B, MTNR1A, FLNA, YWHAQ, GNB1, GNAI3, GNAI2, HSPA5, CANX,
Protein Size: 362

Molekulargewicht: 40 kDa

Gen-ID: 4544

NCBI Accession: NM_005959, NP_005950

UniProt: P49286