SHANK2 Antikörper (C-Term)

Produktnummer ABIN2789712

Der Kaninchen Polyklonal anti-SHANK2 Antikörper wird verwendet zum Nachweis von SHANK2 in Proben von Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen und Pferd. Er wurde validiert für WB.

Kurzübersicht für SHANK2 Antikörper (C-Term) (ABIN2789712)

Target: SHANK2 (SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SHANK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SHANK2 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: SHANK2 Antibody - C-terminal region

Sequenz: PQSPSLNSSQ PTNSADSKKP ASLSNCLPAS FLPPPESFDA VADSGIEEVD

Homologie: Cow: 100%, Dog: 85%, Guinea Pig: 77%, Horse: 100%, Human: 100%, Mouse: 85%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against SHANK2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64052-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu SHANK2

Target: SHANK2 (SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2))

Andere Bezeichnung: SHANK2

Hintergrund:

Background Information: This gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density (PSD). Shank proteins contain multiple domains for protein-protein interaction, including ankyrin repeats, an SH3 domain, a PSD-95/Dlg/ZO-1 domain, a sterile alpha motif domain, and a proline-rich region. This particular family member contains a PDZ domain, a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif. The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain.

Gene Name: SH3 and multiple ankyrin repeat domains 2

Alternative Symbols: SHANK, AUTS17, CORTBP1, CTTNBP1, ProSAP1, SPANK-3

Protein Name: SH3 and multiple ankyrin repeat domains protein 2

Molekulargewicht: 135kDa

Gen-ID: 22941

NCBI Accession: NP_036441

UniProt: Q9UPX8