SHANK2 Antikörper (C-Term)

Produktnummer ABIN2789712

Der Kaninchen Polyklonal Anti-SHANK2-Antikörper wurde für WB validiert. Er ist geeignet, SHANK2 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen und Pferd zu detektieren.

Kurzübersicht für SHANK2 Antikörper (C-Term) (ABIN2789712)

Target: SHANK2 (SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SHANK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SHANK2 Antikörper

Bindungsspezifität: C-Term

Sequenz: PQSPSLNSSQ PTNSADSKKP ASLSNCLPAS FLPPPESFDA VADSGIEEVD

Homologie: Cow: 100%, Dog: 85%, Guinea Pig: 77%, Horse: 100%, Human: 100%, Mouse: 85%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against SHANK2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1254 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SHANK2

Target: SHANK2 (SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2))

Andere Bezeichnung: SHANK2

Hintergrund: This gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density (PSD). Shank proteins contain multiple domains for protein-protein interaction, including ankyrin repeats, an SH3 domain, a PSD-95/Dlg/ZO-1 domain, a sterile alpha motif domain, and a proline-rich region. This particular family member contains a PDZ domain, a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif. The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain.
Alias Symbols: CORTBP1, CTTNBP1, ProSAP1, SHANK, SPANK-3
Protein Interaction Partner: SHARPIN, NLK, LPHN1, DLGAP1, LPHN2, ARHGEF7, BAIAP2, DLG4, BAI2, DNM2, SSTR2, SLC9A3, CTTN, DLGAP3, DLGAP4, DLGAP2, DYNLL2, DYNLL1, MYO5A,
Protein Size: 1254

Molekulargewicht: 135 kDa

Gen-ID: 22941

NCBI Accession: NM_012309, NP_036441