LIMS1 Antikörper (Middle Region)

Produktnummer ABIN2789689

Dieses Anti-LIMS1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von LIMS1 in WB. Geeignet für Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio) und Ziege.

Kurzübersicht für LIMS1 Antikörper (Middle Region) (ABIN2789689)

Target: LIMS1 (LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio), Ziege

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LIMS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-LIMS1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: HLCRPCHNRE KARGLGKYIC QKCHAIIDEQ PLIFKNDPYH PDHFNCANCG

Homologie: Cow: 100%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against LIMS1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human LIMS1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 387 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu LIMS1

Target: LIMS1 (LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1))

Andere Bezeichnung: LIMS1

Hintergrund: The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: PINCH, PINCH1
Protein Interaction Partner: RSU1, UBC, SUMO1, NEDD8, ILK, STUB1, MAPT, MBIP, Hoxa1, HNRNPU, STK11, PARVA, SMURF1, EHMT2, LPXN, NCK2, RBBP8, TMSB4X, TGFBR1, ACP6,
Protein Size: 387

Molekulargewicht: 44 kDa

Gen-ID: 3987

NCBI Accession: NM_001193485, NP_001180414

UniProt: B7Z7R3