BRMS1 Antikörper (C-Term)

Produktnummer ABIN2789686

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch BRMS1 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Hund und Schaf.

Kurzübersicht für BRMS1 Antikörper (C-Term) (ABIN2789686)

Target: BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Hund, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BRMS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BRMS1 Antikörper

Bindungsspezifität: C-Term

Sequenz: HARGSSRSWD SLPPSKRKKA PLVSGPYIVY MLQEIDILED WTAIKKARAA

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 100%, Sheep: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against BRMS1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 290 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu BRMS1

Target: BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))

Andere Bezeichnung: BRMS1

Hintergrund: This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.
Alias Symbols: DKFZp564A063
Protein Interaction Partner: CEP70, NMI, HDAC2, HDAC1, SIN3A, APP, BRMS1L, ING1, HDAC6, HDAC4, TAF1, SMARCE1, SMTN, ARID4A, KPNA5, HSP90AA1, HSPA4, HDAC5, SUDS3, DNAJB6, UBC, SAP25, RELA, NFKB1, HDAC3, LRIF1, RBP1, PFDN5, DNAJB1, SAP30, RBBP4, RBBP7, GOLGB1, EEF1A1,
Protein Size: 290

Molekulargewicht: 34 kDa

Gen-ID: 25855

NCBI Accession: NM_001024957, NP_001020128

UniProt: G5E9I4