FUT3 Antikörper (C-Term)

Produktnummer ABIN2789675

Der Kaninchen Polyklonal anti-FUT3 Antikörper wird verwendet zum Nachweis von FUT3 in Proben von Human und Schwein. Er wurde validiert für WB.

Kurzübersicht für FUT3 Antikörper (C-Term) (ABIN2789675)

Target: FUT3 (Fucosyltransferase 3 (Galactoside 3(4)-L-Fucosyltransferase, Lewis Blood Group) (FUT3))

Reaktivität: Human, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FUT3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FUT3 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: FUT3 Antibody - C-terminal region

Sequenz: RSNYERFLPP DAFIHVDDFQ SPKDLARYLQ ELDKDHARYL SYFRWRETLR

Homologie: Human: 100%, Pig: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against FUT3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63942-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu FUT3

Target: FUT3 (Fucosyltransferase 3 (Galactoside 3(4)-L-Fucosyltransferase, Lewis Blood Group) (FUT3))

Andere Bezeichnung: FUT3

Hintergrund:

Background Information: The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.

Gene Name: Fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)

Alternative Symbols: LE, Les, FT3B, CD174, FucT-III

Protein Name: Galactoside 3(4)-L-fucosyltransferase

Molekulargewicht: 42kDa

Gen-ID: 2525

NCBI Accession: NP_000140

UniProt: P21217