PMM2 Antikörper (N-Term)
Kurzübersicht für PMM2 Antikörper (N-Term) (ABIN2789674)
Target
Alle PMM2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- LRQKIKIGVV GGSDFEKVQE QLGNDVVEKY DYVFPENGLV AYKDGKLLCR
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Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against PMM2. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 246 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PMM2 (Phosphomannomutase 2 (PMM2))
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Andere Bezeichnung
- PMM2
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Hintergrund
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The protein encoded by this gene catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, which is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. Mutations in this gene have been shown to cause defects in glycoprotein biosynthesis, which manifests as carbohydrate-deficient glycoprotein syndrome type I.
Alias Symbols: CDG1, CDG1a, CDGS, PMM 2
Protein Interaction Partner: ACY3, SUMO2, UBC, TAGLN3,
Protein Size: 246 -
Molekulargewicht
- 28 kDa
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Gen-ID
- 5373
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NCBI Accession
- NM_000303, NP_000294
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UniProt
- O15305
Target
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