GIPR Antikörper (N-Term)
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- Target Alle GIPR Antikörper anzeigen
- GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Pferd
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GIPR Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- GFVLRQCGSD GQWGLWRDHT QCENPEKNEA FLDQRLILER LQVMYTVGYS
- Homologie
- Cow: 92%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against GIPR. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product GIPR Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 466 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))
- Andere Bezeichnung
- GIPR (GIPR Produkte)
- Synonyme
- GIPR antikoerper, PGQTL2 antikoerper, GIP-R antikoerper, Gm1081 antikoerper, Gm160 antikoerper, Gippr antikoerper, RATGIPPR antikoerper, gastric inhibitory polypeptide receptor antikoerper, glucagon receptor antikoerper, GIPR antikoerper, LOC100303705 antikoerper, Gipr antikoerper
- Hintergrund
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This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes.
Alias Symbols: MGC126722, PGQTL2
Protein Interaction Partner: LNX1, UBC, GIP,
Protein Size: 466 - Molekulargewicht
- 53 kDa
- Gen-ID
- 2696
- NCBI Accession
- NM_000164, NP_000155
- UniProt
- P48546
- Pathways
- Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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