CASQ2 Antikörper (N-Term)

Produktnummer ABIN2789644

Der Kaninchen Polyklonal anti-CASQ2 Antikörper (ABIN2789644) detektiert spezifisch CASQ2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen und Pferd.

Kurzübersicht für CASQ2 Antikörper (N-Term) (ABIN2789644)

Target: CASQ2 (Calsequestrin 2 (CASQ2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CASQ2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CASQ2 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: CASQ2 Antibody - N-terminal region

Sequenz: DRVVSLSEKN FKQVLKKYDL LCLYYHEPVS SDKVTQKQFQ LKEIVLELVA

Homologie: Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 79%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against CASQ2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63849-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu CASQ2

Target: CASQ2 (Calsequestrin 2 (CASQ2))

Andere Bezeichnung: CASQ2

Hintergrund:

Background Information: The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest.

Gene Name: Calsequestrin 2 (cardiac muscle)

Alternative Symbols: PDIB2

Protein Name: Calsequestrin-2

Molekulargewicht: 46kDa

Gen-ID: 845

NCBI Accession: NP_001223

UniProt: O14958

Pathways: Negative Regulation of Transporter Activity