SCG5 Antikörper (N-Term)

Produktnummer ABIN971664

Der Kaninchen Polyklonal anti-SCG5 Antikörper (ABIN971664) detektiert spezifisch SCG5 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio).

Kurzübersicht für SCG5 Antikörper (N-Term) (ABIN971664)

Target: SCG5 (Secretogranin V (7B2 Protein) (SCG5))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCG5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SCG5 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: SCG5 Antibody - N-terminal region

Sequenz: GPQSIEGGAH EGLQHLGPFG NIPNIVAELT GDNIPKDFSE DQGYPDPPNP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against SCG5. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63847-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu SCG5

Target: SCG5 (Secretogranin V (7B2 Protein) (SCG5))

Andere Bezeichnung: SCG5

Hintergrund:

Background Information: SCG5 acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. SCG5 binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. SCG5 is also required for cleavage of PCSK2 but does not appear to be involved in its folding. SCG5 plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro.

Gene Name: Secretogranin V (7B2 protein)

Alternative Symbols: 7B2, SgV, P7B2, SGNE1

Protein Name: Neuroendocrine protein 7B2

Molekulargewicht: 23kDa

Gen-ID: 6447

NCBI Accession: NP_001138229

UniProt: P05408