SCG5 Antikörper (N-Term)

Produktnummer ABIN2789643

Produktdetails anti-SCG5 Antikörper

Target: SCG5 (Secretogranin V (7B2 Protein) (SCG5))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCG5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GPQSIEGGAH EGLQHLGPFG NIPNIVAELT GDNIPKDFSE DQGYPDPPNP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against SCG5. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 212 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SCG5

Target: SCG5 (Secretogranin V (7B2 Protein) (SCG5))

Andere Bezeichnung: SCG5 (SCG5 Produkte)

Hintergrund: SCG5 acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. SCG5 binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. SCG5 is also required for cleavage of PCSK2 but does not appear to be involved in its folding. SCG5 plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro.
Alias Symbols: 7B2, P7B2, SGNE1, SgV
Protein Interaction Partner: UBQLN1, KHDRBS1, UBQLN4, NR1H2, PCSK2,
Protein Size: 212

Molekulargewicht: 23 kDa

Gen-ID: 6447

NCBI Accession: NM_001144757, NP_001138229

UniProt: P05408