GCKR Antikörper (C-Term)
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- Target Alle GCKR Antikörper anzeigen
- GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GCKR Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- PIALLSLLFR CSITEAQAHL AAAPSVCEAV RSALAGPGQK RTADPLEILE
- Homologie
- Human: 100%, Rat: 79%
- Produktmerkmale
- This is a rabbit polyclonal antibody against GCKR. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product GCKR Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 625 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))
- Andere Bezeichnung
- GCKR (GCKR Produkte)
- Synonyme
- FGQTL5 antikoerper, GKRP antikoerper, GLRE antikoerper, gckr antikoerper, glucokinase regulator antikoerper, glucokinase regulatory protein antikoerper, glucokinase regulator L homeolog antikoerper, GCKR antikoerper, Gckr antikoerper, gckr.L antikoerper
- Hintergrund
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This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).
Alias Symbols: GKRP, FGQTL5
Protein Interaction Partner: CDKN1A, UBC, TRAF2, GCK,
Protein Size: 625 - Molekulargewicht
- 68 kDa
- Gen-ID
- 2646
- NCBI Accession
- NM_001486, NP_001477
- UniProt
- Q14397
- Pathways
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
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